THROMBOPHILIA PROFILE

Specimen Required
Whole blood and plasma are required. Whole blood: Draw blood in a yellow ACD and send 6.0 mL whole blood (3.0 mL minimum) room temperature.
Plasma: Draw blood in 3-4 light blue 3.2% sodium citrate tubes. See appendices for coagulation test collection instructions. Send 6.0 mL plasma (5.0 mL minimum) frozen in 1.0 mL aliquots in 6 plastic screw-capped vials.
Specimen must be drawn prior to initiation of anticoagulants and thrombolytic therapy.

Alternate Specimen
Whole blood: EDTA or 3.2% sodium citrate

Rejection Criteria
Gross hemolysis, lipemia or icteria

Methodology
Latex Immunoassay, Chromogenic Assay, Direct Mutation Analysisi, Clauss, Optical Clot-Based

Stability
Plasma: Room Temperature: Unacceptable; Refrigerated: Unacceptable; Frozen: 14 days
Whole blood: Room Temperature: 7 days; Refrigerated: 14 days; Frozen: 14 days

Reference Range
By report

Performed
Monday-Friday

Turnaround Time5-10 days
Test CodeAATHR
CPT-4 Code (s)
81240 F2 (prothrombin, coagulation factor II) eg, hereditary hypercoagulability) gene analysis, 20210G->A variant; 85300 AT activity: 85303 Protein C activity; 85306 Protein S antigen, free; 85307 Activated protein resistance V; 85379 D-Dimer; 85384 Fibrinogen; 85390 26-Special coagulation interpretation; 85610 PT, 85613 DRVVT; 85670 Thrombin time; 85730 APTT, plus others as appropriate, at additional charges
ZB27J
LOINC Codes
27811-9

Warde
Medical
Laboratory